Understanding Breast Cancer Treatment

Paget’s Disease: A Rare Form of Breast Cancer

Seldom does a week go by when some form of breast cancer isn’t mentioned in the news, but when was the last time you heard anything about Paget’s disease? In fact, you may have never heard anything about it. This is not surprising because it’s quite rare. While the disease is very uncommon, it is very important to know the symptoms as it can be misdiagnosed as a dermatological condition.

What is Paget’s Disease?

Paget’s disease is a rare type of breast cancer that develops in and around the nipple and areola. This form of cancer should not be confused with other diseases named after Paget, which are unrelated. Typically, it occurs in women over the age of 50, but on rare occasions can be diagnosed in younger women. Most women diagnosed with Paget’s disease also have some form of underlying breast cancer, but it can also occur on its own.

What are the Symptoms?

The symptoms of Paget’s disease may resemble other skin conditions so it is possible that it can be misdiagnosed. A variety of symptoms may include:

Irritation or redness
Flaking or scaly skin on the nipple
Tingling or itching
Burning
Discharge from the nipple
A flattened or inverted nipple

Early on, symptoms of the disease can appear to subside, but this can be misleading as the disease does not simply go away on its own. Often there is a lump that can be felt under the nipple or areola area. It usually develops in only one breast.

How is Paget’s Disease Diagnosed?

If Paget’s disease is suspected, there are several tests that may be performed. The first step is usually a breast exam to check for lumps and changes in the skin of the nipple and areola. A biopsy may follow where a small amount of tissue is removed to check for the presence of Paget cells. If there is nipple discharge, a sample will also be tested for the disease. As there is a good chance that underlying breast cancer also exists, a mammogram is performed to make a complete diagnosis.

Treatment for Paget’s Disease

Treatment for this disease is typically surgery, either a lumpectomy or mastectomy depending on the presence of underlying breast cancer. Lymph nodes are checked for the presence of cancer cells, as well. Additional treatment (adjuvant therapy) may be given after surgery depending on the type of cancer and whether or not it has spread. Treatments can include radiation, chemotherapy or hormone therapy. Prognosis for Paget’s disease is similar to other types of breast cancer.

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